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Examples: Omeprazole (Prilosec), Esomeprazole (Nexium)
Why they harm kidneys: Linked to chronic kidney disease and acute interstitial nephritis with long-term use.
Still sold because: They treat acid reflux and ulcers effectively. Risk increases with prolonged or unnecessary use.
3. Certain Antibiotics
Examples: Gentamicin, Vancomycin, Amphotericin B
Why they harm kidneys: They can be directly toxic to kidney tissues.
Still sold because: They’re critical for treating serious infections; risk is managed by close monitoring.
4. ACE Inhibitors and ARBs
Examples: Lisinopril, Enalapril, Losartan, Valsartan
Why they harm kidneys: Can reduce kidney filtration in certain patients (especially dehydrated or with renal artery stenosis).
Still sold because: They are lifesaving for heart failure, high blood pressure, and diabetic kidney disease—often protect kidneys in the long term.
5. Diuretics (Water Pills)
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