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Preheat the air fryer to 400°F.
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Brush one side of each tortilla lightly with olive oil. Be sure to get all the way to the edges.
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Spread 1 tablespoon sauce over the middle of one tortilla, then top with ¼ cup cheese. Cover with second tortilla and repeat with the remaining sauce and cheese. Top with pepperoni and oregano.
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Lightly brush the air fryer basket with any remaining olive oil and transfer the pizza to the air fryer basket. Cook 6 minutes.
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Carefully remove the pizza with a spatula and let cool slightly before slicing.